Endocrine Abstracts

Angiotensin II receptor antagonists (ARB) decrease plasma aldosterone concentration (PAC) for cardiovascular protection. However, long-term ARB therapy increases PRA and PAC, which is known as ‘aldosterone escape.’ β-Blockers are the noble antihypertensive agents to decrease PRA. Nevertheless, little is known about the effect of coadministration of both agents on PRA and aldosterone escape. The study was designed to compare the effects of adding atenolol (β...